Testosterone: MedlinePlus Drug Information

Online Testosterone Replacement Therapy

Testosterone supplementation using injectable testosterone is one of the most popular forms of TRT for a variety of reasons. Testosterone treatment using injections is typically performed intramuscularly or subcutaneously. Underlying causes of low testosterone such as hypothyroidism, hemochromatosis, sleep disturbance and pituitary adenomas can be effectively treated so that testosterone therapy can be avoided. Up to 20% of men properly evaluated will have a correctable cause for their testosterone deficiency. The normal reference range for testosterone – amsterdam-online.nl, will vary between labs but generally runs between 300-1,200 ng/dL for total testosterone.

If you are taking hormone replacement therapy, regular follow-up appointments with your doctor are important. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. Warming and shaking the vial should redissolve any crystals that may have formed during storage at temperatures lower than recommended. The suggested dosage for DEPO-Testosterone Injection varies depending on the age, sex, and diagnosis of the individual patient. Dosage is adjusted according to the patient’s response and the appearance of adverse reactions. Drug dependence in individuals using approved doses of testosterone for approved indications has not been documented. Safety and effectiveness in pediatric patients below the age of 12 years have not been established.

Men who have prostate cancer or breast cancer should not take testosterone replacement therapy. Nor should men who have severe urinary tract problems, untreated severe sleep apnea or uncontrolled heart failure. All men considering testosterone replacement therapy should undergo a thorough prostate cancer screening — a rectal exam and PSA test — prior to starting this therapy. The long-acting form of injectable testosterone is known as Aveed™ (testosterone undecanoate). Once Aveed™ establishes healthy baseline levels, injections are only required every 10 weeks.

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Unusual presentations such as dark urine can occur if a clot forms in the renal or hepatic veins. Treatment of hair loss may include topical Minoxidil, finasteride (Propecia), PRP injections and hair transplant. I am generally not a fan of finasteride due to the risk of sexual side effects and post-finasteride syndrome. Even topical finasteride will get systemically absorbed to some extent and I’ve seen a case of PFS due to topical finasteride applied to the scalp.

This means that all testosterone formulations should treat low T symptoms once normal testosterone values are restored. For example, topical testosterone often has very inconsistent absorption in men. Compounded testosterone creams and gels are even more inconsistent in their skin transmission. Oral testosterone absorption can be affected by certain foods and must be taken with a fatty meal. Men who present with low T symptoms and/or signs of hypogonadism warrant a thorough medical evaluation. This should include a complete medical history, physical examination and laboratory assessment.

Men with low T often struggle with weight loss leading to an increased risk of obesity. Testosterone booster injections, a form of testosterone replacement therapy (TRT), aim to replenish testosterone levels and restore robust male vitality. However, the variety of options available, each with its potential risks and benefits, can make the choice confusing.

When men are treated with excess testosterone, anxiety can actually be worsened. This can occur in men treated medically to abnormally high testosterone levels as well as in men abusing anabolic steroids. Men with low testosterone levels typically report lower quality of life scores. Symptoms contributing to these lower QoL scores include fatigue, lack of motivation, irritability, dysphoria, mood swings, reduced sexual performance, cognitive impairment and even negative work performance. If hypertension develops in a patient who recently started testosterone replacement therapy, a dose reduction may remedy the situation.